Volume 2 (Issue 1)

pp. 1-12

Open Access

Review paper

Spice Bioactive Compounds versus Lifestyle Disorders

Uma Maheshwari Srinivasa, Madeneni Madhava Naidu*

UMS, MMN: Department of Spices and Flavor Sciences, CSIR-CFTRI, Mysuru - 570020, Karnataka, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad - 201002, UP, India


*Corresponding author: Madeneni Madhava Naidu; Email: mmnaidu@cftri.res.in

DOI:

Received: 

22 January 2022

Published:

04 March 2022

Cite as: Srinivasa, U. M,  Naidu, M. M. (2022). Spice Bioactive Compounds versus Lifestyle Disorders. Inventum Biologicum, 2 (1), 1-12.

Abstract

Spices play a significant role in food flavoring and as adjuncts in traditional medicine. Recent developments have shown that the spice extracts and their bioactive molecules play a vital part in either preventing, ameliorating or curing different diseases or disorders. Lifestyle diseases have increased globally and are a significant public health challenge to every country. Cardiovascular diseases and cancer, the first and second leading cause of death, respectively, and diabetes and obesity, are on par through the exponential increase in the incidents. Though pharmaceuticals strive hard to be active and efficient, their synergistic effect makes them partially unreliable. This surges the need for natural therapeutic medicines to outmaneuver the existing global health burden. Hence, nutrition-based medicine is the present vogue used to target the pathogeny and their complications. Here we illustrate the most critical investigations which have been validated to be potential in combating these complications through rhizome spice (turmeric and ginger), seed spice (fenugreek), seed/leaf spice (coriander) and their bioactive components. Drug safety is also the primary concern of medical therapy; hence the usage is recommended in the safety range without surpassing the toxicity levels. Nutraceuticals and functional foods are a promising source of natural medicines for controlling various health complications used in proper concentrations and methods. In this paper, selective spices and their effects and the mechanisms of action taken by them to circumvent the significant lifestyle diseases have been discussed.

Keywords:

Coriander, Fenugreek, Ginger, Lifestyle diseases, Safety, Spices, Turmeric

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Funding Information

Uma Maheshwari is thankful to DBT, New Delhi, for the Junior Research Fellowship.

Declaration of Conflict

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.